Since 2020, aggregated from related topics
Tumor necrosis factor-alpha (TNF-α) is a cytokine produced primarily by immune cells in response to inflammation or infection. It plays a crucial role in regulating immune responses, triggering cell death in tumor cells, and promoting inflammation. TNF-α has been implicated in various diseases, including arthritis, inflammatory bowel disease, and cancer. Research in this area focuses on understanding the mechanisms by which TNF-α functions, developing therapies that target TNF-α, and exploring its potential as a biomarker for disease.